Table 1 Accuracy, sensitivity, and specificity with CNVs and viruses.

From: Analytical and clinical validation of CancerMaster, an automated targeted NGS panel, for tumor-only precision oncology

Genes

Positive

Negative

Accuracy

Sensitivity

Specificity

ERBB2 (n = 143)

40

103

91.6%

70%

100%

MET (n = 59)

17

42

98.3%

94.1%

100%

EGFR (n = 96)

11

85

92.7%

45.5%

98.8%

FGFR2 (n = 4)

4

0

100%

100%

NA

EBV (n = 110)

8

102

96.4%

87.5%

97.1%

HPV (n = 9)

7

2

77.8%

71.4%

100%

  1. CNV, copy number variant; ERBB2, (HER2, Receptor tyrosine-protein kinase erbB-2); MET, MET proto-oncogene; EGFR, Epidermal growth factor receptor; FGFR2, Fibroblast growth factor receptor 2; EBV, Epstein-Barr virus; HPV, human papillomavirus.
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