Table 2 Demographic data and clinical characteristics of children with acute IM.
From: Altered expression of the CD26/ADA axis in immune-mediated inflammation of infectious mononucleosis
Parameters | IM (n = 30) | Control (n = 30) | P value |
|---|---|---|---|
Age (mean ± SD, year) | 5.5 ± 2.4 | 5.7 ± 3.2 | 0.739 |
Male (n,%) | 18(60.0) | 12(40.0) | 0.200 |
WBC count (mean ± SD,×109/L) | 14.5 ± 6.5 | 7.7 ± 2.5 | <0.01 |
Lym count (mean ± SD,×109/L) | 9.9 ± 4.9 | 3.9 ± 2.0 | <0.01 |
IgA (mean ± SD, g/L) | 2.1 ± 1.0 | 0.8 ± 0.7 | <0.01 |
IgG (mean ± SD, g/L) | 11.7 ± 3.3 | 7.8 ± 3.4 | <0.01 |
IgM (mean ± SD, g/L) | 2.2 ± 1.8 | 1.1 ± 0.6 | 0.011 |
Lymphocytes subgroups | <0.01 | ||
CD3+ (mean ± SD,%) | 81.1 ± 9.1 | 69.5 ± 6.7 | <0.01 |
CD3+ (mean ± SD, cells/µL) | 7944 ± 3911 | 2733 ± 957 | <0.01 |
CD3+ CD4+ (mean ± SD,%) | 16.7 ± 4.9 | 52.5 ± 6.0 | 0.002 |
CD3+ CD4+ (mean ± SD, cells/µL) | 1547 ± 693 | 2036 ± 673 | <0.01 |
CD3+ CD8+ (mean ± SD,%) | 54.3 ± 11.2 | 24.1 ± 6.1 | <0.01 |
CD3+ CD8+ (mean ± SD, cells/µL) | 5515 ± 3388 | 1021 ± 457 | <0.01 |
CD4+/CD8+ | 0.3 ± 0.1 | 1.8 ± 0.6 | <0.01 |
