Fig. 3
The pro-proliferative factors in PDLS-MCL boost cell growth and are associated with increased levels of EZH2 but decreased levels of MALAT1. (A) Cell growth is significantly higher in PDLS of both cases when pro-proliferative cases are present in the media (P < 0.0001). (B) MALAT1 expression significantly increased in both MCL cases cultured when cultured without pro-proliferative factors (P = 0.020 in MCL#1 and P = 0.021 in MCL#2. (C) EZH2 levels increased in both MCL cases after growing with pro-proliferative factors (MCL#1 P = 0.0047 and MCL#2 P < 0.0001). RQ: Relative Quantification. Median values and interquartile range are depicted.
