Fig. 5 | Scientific Reports

Fig. 5

From: The expression of MALAT1 long non-coding RNA is associated with good prognosis in mantle cell lymphoma

Fig. 5

EZH2 inhibition using GSK126 significantly upregulated MALAT1 expression in three SOX11 positive MCL PDLS growing with or without pro-proliferative factors. The inhibitor was used at two 10-fold different concentrations, and we could observe a highly significant increase in MALAT1 expression upon the treatment with the highest dose of the inhibitor in all cases with pro-proliferative factors and nearly all in their absence.

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