Fig. 5
From: Metapanax delavayi extract as a neurocutaneous modulator via CRHR1/POMC/MC1R signaling
MDE inhibits neurogenic inflammation by inhibiting CRHR1/POMC/MC1R signaling pathway. (A-C) RT-qPCR analysis was performed to assess the effects of MDE on mRNA expression levels of CRHR1, POMC, and MC1R (N = 4). (D-F) Quantitative density analysis of CRHR1, MC1R and POMC (N = 3). (G) Expression of CRHR1, MC1R and POMC was probed by Western blot. Data are presented as mean ± SEM. p value using the one-way ANOVA. * p ≤ 0.05, ** p ≤ 0.01 versus control; # p ≤ 0.05, ## p ≤ 0.01 versus capsaicin-induced.
