Table 1 Selected CTL epitopes of hMPV, RSV, and IAV used in the proposed chimeric multi-epitope subunit vaccine.
Virus | Protein | Peptide sequence | Peptide position | Conserved region | Combined score | Antigenicity score | Toxicity | Allergenicity |
|---|---|---|---|---|---|---|---|---|
hMPV | Fusion | LSVLRTGWY | 35–44 | Yes | 1.6130 | 0.8622 | NO | Non-allergenic |
FSDNAGITP | 88–97 | Yes | 0.8963 | 0.7563 | NO | Non-allergenic | ||
RSV | Fusion | NIDIFNPKY | 382–391 | Yes | 2.5413 | 0.7826 | NO | Non-allergenic |
LIAVGLLLY | 540–549 | Yes | 2.3421 | 0.8288 | NO | Non-allergenic | ||
IAV | Neuraminidase | WTSASSISF | 421–430 | Yes | 1.5752 | 1.0334 | NO | Non-allergenic |
ELNAPNSHY | 252–261 | Yes | 1.1526 | 0.1266 | NO | Non-allergenic |