Table 1 Selected CTL epitopes of hMPV, RSV, and IAV used in the proposed chimeric multi-epitope subunit vaccine.

From: Immunoinformatics based designing of a broad-spectrum multi-epitope vaccine against co-infection of human metapneumovirus, respiratory syncytial virus, and influenza A virus

Virus

Protein

Peptide

sequence

Peptide position

Conserved region

Combined score

Antigenicity

score

Toxicity

Allergenicity

hMPV

Fusion

LSVLRTGWY

35–44

Yes

1.6130

0.8622

NO

Non-allergenic

FSDNAGITP

88–97

Yes

0.8963

0.7563

NO

Non-allergenic

RSV

Fusion

NIDIFNPKY

382–391

Yes

2.5413

0.7826

NO

Non-allergenic

LIAVGLLLY

540–549

Yes

2.3421

0.8288

NO

Non-allergenic

IAV

Neuraminidase

WTSASSISF

421–430

Yes

1.5752

1.0334

NO

Non-allergenic

ELNAPNSHY

252–261

Yes

1.1526

0.1266

NO

Non-allergenic