Table 1 Characteristics of patients who received glycopeptides and beta-lactams.

From: Association of antibiotic type and timing with sepsis mortality using target trial emulation

Characteristic

Overall, N = 3,510

Glycopeptides, N = 1,653

Beta-lactams, N = 1,857

p-value

Age

65.35 ± 16.84

64.98 ± 17.32

65.67 ± 16.40

0.3

Sex

   

0.004

Female

1,483 (42%)

741 (45%)

742 (40%)

 

Male

2,027 (58%)

912 (55%)

1,115 (60%)

 

Weight_admit

82.27 ± 23.90

82.93 ± 25.19

81.69 ± 22.68

0.4

CVD

2,634 (75%)

1,249 (76%)

1,385 (75%)

0.5

Liver_disease

590 (17%)

295 (18%)

295 (16%)

0.12

Renal_disease

632 (18%)

335 (20%)

297 (16%)

0.001

Thrombosis

169 (4.8%)

99 (6.0%)

70 (3.8%)

0.002

Malignant_cancer

414 (12%)

215 (13%)

199 (11%)

0.036

COPD

418 (12%)

222 (13%)

196 (11%)

0.009

CCI

5.49 ± 2.90

5.62 ± 2.96

5.37 ± 2.84

0.005

SOFA_score

3.72 ± 1.93

3.93 ± 2.03

3.53 ± 1.82

< 0.001

SAPS II_score

40.70 ± 13.97

42.80 ± 14.17

38.83 ± 13.53

< 0.001

RRT

170 (4.8%)

115 (7.0%)

55 (3.0%)

< 0.001

Mechanical_ventilation

2,272 (65%)

1,075 (65%)

1,197 (64%)

0.7

Septic_shock

909 (26%)

618 (37%)

291 (16%)

< 0.001

  1. CVD, cardiovascular disease; COPD, chronic obstructive pulmonary disease; CCI, Charlson Comorbidity Index; SOFA_score, Sequential Organ Failure Assessment score; SAPS II_score, Simplified Acute Physiology Score II score; RRT, renal replacement therapy. Continuous variables are presented as means ± SD and categorical variables are presented as counts (percentages).