Table 1 Characteristics of patients who received glycopeptides and beta-lactams.
From: Association of antibiotic type and timing with sepsis mortality using target trial emulation
Characteristic | Overall, N = 3,510 | Glycopeptides, N = 1,653 | Beta-lactams, N = 1,857 | p-value |
|---|---|---|---|---|
Age | 65.35 ± 16.84 | 64.98 ± 17.32 | 65.67 ± 16.40 | 0.3 |
Sex | 0.004 | |||
Female | 1,483 (42%) | 741 (45%) | 742 (40%) | |
Male | 2,027 (58%) | 912 (55%) | 1,115 (60%) | |
Weight_admit | 82.27 ± 23.90 | 82.93 ± 25.19 | 81.69 ± 22.68 | 0.4 |
CVD | 2,634 (75%) | 1,249 (76%) | 1,385 (75%) | 0.5 |
Liver_disease | 590 (17%) | 295 (18%) | 295 (16%) | 0.12 |
Renal_disease | 632 (18%) | 335 (20%) | 297 (16%) | 0.001 |
Thrombosis | 169 (4.8%) | 99 (6.0%) | 70 (3.8%) | 0.002 |
Malignant_cancer | 414 (12%) | 215 (13%) | 199 (11%) | 0.036 |
COPD | 418 (12%) | 222 (13%) | 196 (11%) | 0.009 |
CCI | 5.49 ± 2.90 | 5.62 ± 2.96 | 5.37 ± 2.84 | 0.005 |
SOFA_score | 3.72 ± 1.93 | 3.93 ± 2.03 | 3.53 ± 1.82 | < 0.001 |
SAPS II_score | 40.70 ± 13.97 | 42.80 ± 14.17 | 38.83 ± 13.53 | < 0.001 |
RRT | 170 (4.8%) | 115 (7.0%) | 55 (3.0%) | < 0.001 |
Mechanical_ventilation | 2,272 (65%) | 1,075 (65%) | 1,197 (64%) | 0.7 |
Septic_shock | 909 (26%) | 618 (37%) | 291 (16%) | < 0.001 |