Fig. 2 | Scientific Reports

Fig. 2

From: Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8

Fig. 2

mRNA expression of fibrosis-related genes in HOXC8-imESCs. Real-time RT-PCR analysis of the fibrosis-related gene mRNA expression in Control-imESCs and HOXC8-imESCs. The analysis included the following genes: COL1A1 and COL1A2 (collagen), MMP1, MMP2, and MMP14 (matrix metalloproteinases), and TIMP1, TIMP2, and TIMP3 (tissue inhibitor of metalloproteinases). Experiments were performed three times in triplicate. GAPDH was used as an internal control. The relative expression levels in HOXC8-imESCs were normalized to Control-imESCs as 1 and are presented as mean ± SD. *p < 0.05

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