Correction to: Scientific Reports https://doi.org/10.1038/s41598-025-98085-x, published online 18 April 2025

The original version of this Article contained an error in Figure 2 and Figure 4, where during figure assembly, the panels in Figure 2C, Figure 4C and Figure 4F were incorrectly duplicated.

The original Figure 2 and 4 and its accompanying legend appear below.

Fig. 2
Fig. 2
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PDZK1 suppresses OXA chemosensitivity of hepatocellular carcinoma. A Western Blot (cropped images) analysis of PDZK1 expression in PDZK1-overexpressed and control HepG2 cells. B Cell viability of OXA treated PDZK1-overexpressed and control HepG2 cells. Repeated measurement ANOVA, * p < 0.05. C Transwell invasion assay of OXA treated PDZK1-overexpressed and control HepG2 cells. Unpaired t-test, ns represents p>0.05, * p < 0.05. D Western Blot (cropped images) analysis of PDZK1 expression of PDZK1 stable overexpression (Huh7-PDZK1-OE) and control (Huh7-PDZK1-NC) cells. E Cell viability and IC50 value of Huh7-PDZK1-NC (left) and Huh7-PDZK1-OE (right) cells treated with OXA concentration gradient for 48 h. F Transwell migration and invasion assay of OXA-treated Huh7-PDZK1-NC and Huh7-PDZK1-OE cells. Unpaired t-test, *** p < 0.001. G Western Blot (cropped images) analysis of PDZK1 expression in siPDZK1 and control HepG2 cells. H Cell viability of OXA treated siPDZK1 and control cells. Repeated measurement ANOVA, *** p < 0.001. I Transwell invasion assay of OXA treated siPDZK1 and control cells. Unpaired t-test, ns represents p>0.05, *** p < 0.001. J Subcutaneous transplantation tumor model detection of Huh7-NC and Huh7-PDZK1 chemotherapy sensitivity to OXA. Two-way ANOVA, * p < 0.05, ** p < 0.01, *** p < 0.001.

Fig. 4
Fig. 4
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PDZK1 inhibits OXA chemosensitivity through MRP2. A MRP2 protein expression levels as shown by Western Blot (cropped images) in transient MRP2 overexpression HepG2 cells. B Cell viability of OXA treated MRP2-overexpressed and control HepG2 cells. Repeated measurement ANOVA, * p < 0.05. C Transwell invasion assay of OXA treated MRP2-overexpressed and control HepG2 cells. Unpaired t-test, ns represents p>0.05, ** p < 0.01. D MRP2 protein expression levels as shown by Western Blot (cropped images) in siMRP2 and control HepG2 cells. E Cell viability of OXA treated siMRP2 and control HepG2 cells. Repeated measurement ANOVA, **p < 0.01. F Transwell invasion assay of OXA treated siMRP2 and control HepG2 cells. Unpaired t-test, ns represents p>0.05, **** p < 0.0001. G Western Blot (cropped images) analysis of PDZK1 and MRP2 expression in co-transfection of PDZK1 small interfering RNA and MRP2 plasmid and control HepG2 cells. H Cell viability were used to detected cell function of sicontrol, siPDZK1 and siPDZK1 + MRP2. Post-hoc test with repeated measurement ANOVA., *p < 0.05, **p < 0.01, ***p < 0.001. I Transwell invasion assay were used to detected cell function of sicontrol, siPDZK1 and siPDZK1 + MRP2. Post-hoc test with one-way ANOVA, ns represents p>0.05, **** p < 0.0001. J Wound healing assay were used to detected cell function of sicontrol, siPDZK1 and siPDZK1 + MRP2. Post-hoc test with repeated measurement ANOVA, ns represents p>0.05, * p < 0.05, **p < 0.01.

The original Article has been corrected.