Table 1 The basic characteristics of the AECOPD group, stable COPD, heavy—smoking group, and healthy control group.

From: Diagnostic and prognostic value of serum miR-155 in chronic obstructive pulmonary disease

 

AECOPD(n = 29)

stable COPD (n = 30)

heavy- smoking (n = 31)

healthy control (n = 27)

p

Age

70.03 ± 8.11

69.57 ± 6.76

67.52 ± 7.72

67.44 ± 6.70

0.053

Sex

Male, n (%)

27(93.1%)

28(93.3%)

28(90.3%)

21(77.8%)

0.169

Female, n (%)

2(6.9%)

2(6.7%)

3(9.7%)

6(22.2%)

 

BMI

23.38 ± 2.88

22.80 ± 2.61

23.74 ± 2.40

24.51 ± 2.36

0.092

Smoking status

Never, n (%)

0(0%)

0(0%)

0(0%)

27(100%)

 

Former, n (%)

24(82.75%)

22(73.33%)

0(0%)

0(0%)

0.000

Current, n (%)

5(17.24%)

8(26.67%)

31(100%)

0(0%)

 

FEV1%pred

30.0

(25.7, 43.6)*#&

65.7(40.9, 86.1)*#

101.5(91.8, 112.3)

97.5(87.0, 109.5)

0.000

Comorbidities

Cardiovascular disease, n (%)

10(34.5%)

4(13.3%)

5(16.1%)

4(14.8%)

0.142

Cerebrovascular disease, n (%)

2(6.9%)

0(0.0%)

1(3.2%)

2(7.4%)

0.300

Diabetes mellitus, n (%)

4(13.8%)

4(13.3%)

4(12.9%)

4(14.8%)

0.997

Connective tissue disease, n (%)

1(3.4%)

1(3.3%)

1(3.2%)

2(7.4%)

0.862

Gastroesophageal reflux, n (%)

2(6.9%)

1(3.3%)

1(3.2%)

2(7.4%)

0.822

GOLD stages

I, n (%)

3(10.3%)

7(23.3%)

  

0.299

II, n (%)

2(6.9%)

8(26.7%)

  

0.080

III, n (%)

11(37.9%)

6(20.0%)

  

0.158

IV, n (%)

13(44.8%)

9(30.0%)

  

0.288

ABE groups

A, n (%)

2(6.9%)

6(20.0%)

  

0.254

B, n (%)

8(29.6%)

11(36.7%)

  

0.779

E, n (%)

19(65.5%)

13(43.3%)

  

0.087

  1. Data are presented as mean ± standard deviation or median (IQR). BMI, body mass index; AECOPD, acute exacerbation of chronic obstructive pulmonary disease; COPD, chronic obstructive pulmonary disease; IQR, interquartile range. “*” indicates significant difference compared to healthy controls (P < 0.05). “#” indicates significant difference compared to heavy- smoking (P < 0.05). “&” indicates significant difference compared to Stable COPD (P < 0.05).