Table 2 Association between SLD and OSA.

From: Association between metabolic dysfunction-associated steatotic liver disease and obstructive sleep apnea: a nationwide retrospective cohort study

Group

Number

Events

Follow-up duration (person-years)

Incidence rate (per 1000 person-years)

Crude HR (95% CIs, P-value)

Adjusted HR (95% CIs, P-value)*

Absolute risk difference [95% CIs]**

No SLD without CMRF

26,067

79

248,970.6

0.32

1 (Reference)

1 (Reference)

Reference

No SLD with CMRF

138,580

428

13,15,323.0

0.33

1.03 (0.81–1.30, p = 0.839)

1.18 (0.93–1.50, p = 0.179)

0.05% [-0.02% to 0.13%]

MASLD without alcohol

50,526

194

479,543.9

0.40

1.27 (0.98–1.65, p = 0.070)

1.46 (1.12–1.91, p = 0.006)

0.14% [0.04% to 0.23%]

MASLD with alcohol

38,207

251

360,506.2

0.70

2.20 (1.71–2.84, p < 0.001)

1.52 (1.17–1.98, p = 0.002)

0.16% [0.06% to 0.24%]

MetALD

12,072

73

113,750.7

0.64

2.03 (1.48–2.79, p < 0.001)

1.40 (1.01–1.94, p = 0.042)

0.12% [0% to 0.23%]

MASLD without alcohol

50,526

194

479,543.9

0.40

1 (Reference)

1 (Reference)

Reference

MASLD with alcohol

38,207

251

360,506.2

0.70

1.72 (1.43–2.08, p < 0.001)

1.00 (0.82–1.24, p = 0.964)

0.02% [-0.06% to 0.11%]

MetALD

12,072

73

113,750.7

0.64

1.59 (1.21–2.08, p = 0.001)

0.92 (0.69–1.22, p = 0.556)

-0.02% [-0.13% to 0.12%]

  1. *The model was adjusted for age, sex, income level, residence area, Charlson comorbidity index, hemoglobin level, glomerular filtration rate, and smoking and regular exercise status.
  2. **Absolute risk differences were calculated based on cumulative incidence estimates from the fully adjusted Cox models.