Table 2 Association between SLD and OSA.
Group | Number | Events | Follow-up duration (person-years) | Incidence rate (per 1000 person-years) | Crude HR (95% CIs, P-value) | Adjusted HR (95% CIs, P-value)* | Absolute risk difference [95% CIs]** |
|---|---|---|---|---|---|---|---|
No SLD without CMRF | 26,067 | 79 | 248,970.6 | 0.32 | 1 (Reference) | 1 (Reference) | Reference |
No SLD with CMRF | 138,580 | 428 | 13,15,323.0 | 0.33 | 1.03 (0.81–1.30, p = 0.839) | 1.18 (0.93–1.50, p = 0.179) | 0.05% [-0.02% to 0.13%] |
MASLD without alcohol | 50,526 | 194 | 479,543.9 | 0.40 | 1.27 (0.98–1.65, p = 0.070) | 1.46 (1.12–1.91, p = 0.006) | 0.14% [0.04% to 0.23%] |
MASLD with alcohol | 38,207 | 251 | 360,506.2 | 0.70 | 2.20 (1.71–2.84, p < 0.001) | 1.52 (1.17–1.98, p = 0.002) | 0.16% [0.06% to 0.24%] |
MetALD | 12,072 | 73 | 113,750.7 | 0.64 | 2.03 (1.48–2.79, p < 0.001) | 1.40 (1.01–1.94, p = 0.042) | 0.12% [0% to 0.23%] |
MASLD without alcohol | 50,526 | 194 | 479,543.9 | 0.40 | 1 (Reference) | 1 (Reference) | Reference |
MASLD with alcohol | 38,207 | 251 | 360,506.2 | 0.70 | 1.72 (1.43–2.08, p < 0.001) | 1.00 (0.82–1.24, p = 0.964) | 0.02% [-0.06% to 0.11%] |
MetALD | 12,072 | 73 | 113,750.7 | 0.64 | 1.59 (1.21–2.08, p = 0.001) | 0.92 (0.69–1.22, p = 0.556) | -0.02% [-0.13% to 0.12%] |