Fig. 1

A. Comparison of the herpesvirus antibody titers between the different cohorts at different decades of age: <40 years (PPMS: n = 27; RRMS: n = 172; SPMS: n = 21; HC: n = 96), between 40 and 50 years (PPMS: n = 47; RRMS: n = 77; SPMS: n = 38; HC: n = 48) and > 50 years (PPMS: n = 84; RRMS: n = 17; SPMS: n = 19; HC: n = 17). Median and interquartile range (P25 and P75) are shown. * (p < 0.05); ** (p < 0.005); *** (p < 0.0005). B. Evolution of the herpesvirus antibody prevalences in each one of the cohorts along different decades of age (< 40 years, between 40 and 50 years and with > 50 years).