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Biomechanical evaluation of 3D-printed porous lattice versus solid mandibular implants: an in vitro study
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  • Published: 27 April 2026

Biomechanical evaluation of 3D-printed porous lattice versus solid mandibular implants: an in vitro study

  • Hao Zhang1,
  • Jui-Ting Hsu2,
  • Lih-Jyh Fuh1,3 &
  • …
  • Heng-Li Huang1,4 

Scientific Reports (2026) Cite this article

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Subjects

  • Biotechnology
  • Engineering
  • Health care
  • Materials science
  • Medical research

Abstract

Segmental mandibular reconstruction is challenging. This in-vitro study compared the biomechanics of two 3D-printed porous Ti-6Al-4 V implants (Quad-diametral-cross, Hex-vase) versus a solid implant using a dual-material 3D-printed mandibular model and strain gauges. A 100 N static load was applied. Under eccentric loading, the solid implant generated extremely high tensile strain (871.67 µε), while porous designs reduced peak strains. The Hex-vase design transmitted the highest compressive strain (-795.85 µε), 65% greater in magnitude than the solid, suggesting improved mechanical stimulus transfer to peri-implant bone. The QDC design provided a moderate environment, suitable for compromised bone. Porous implants are biomechanically superior, offering customizable solutions to mitigate stress shielding.

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Funding

This study was supported by academic and government organizations: China Medical University (CMU113-MF-65) and National Science and Technology Council (NSTC 113-2221-E-039 -002 -MY3) in Taiwan.

Author information

Authors and Affiliations

  1. School of Dentistry, China Medical University, Taichung, Taiwan

    Hao Zhang, Lih-Jyh Fuh & Heng-Li Huang

  2. Department of Biomedical Engineering, China Medical University, Taichung, Taiwan

    Jui-Ting Hsu

  3. Department of Dentistry, China Medical University Hospital, Taichung, Taiwan

    Lih-Jyh Fuh

  4. Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan

    Heng-Li Huang

Authors
  1. Hao Zhang
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  2. Jui-Ting Hsu
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  3. Lih-Jyh Fuh
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  4. Heng-Li Huang
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Corresponding author

Correspondence to Heng-Li Huang.

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Competing interests

The authors declare no competing interests.

Ethical approval

The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Institutional Review Board of China Medical University Hospital (protocol code: CMUH110-REC2-247).

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Cite this article

Zhang, H., Hsu, JT., Fuh, LJ. et al. Biomechanical evaluation of 3D-printed porous lattice versus solid mandibular implants: an in vitro study. Sci Rep (2026). https://doi.org/10.1038/s41598-026-50741-6

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  • Received: 01 February 2026

  • Accepted: 23 April 2026

  • Published: 27 April 2026

  • DOI: https://doi.org/10.1038/s41598-026-50741-6

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Keywords

  • Mandibular reconstruction
  • Porous implant
  • Stress shielding
  • Additive manufacturing
  • Strain gauge
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