Abstract
Segmental mandibular reconstruction is challenging. This in-vitro study compared the biomechanics of two 3D-printed porous Ti-6Al-4 V implants (Quad-diametral-cross, Hex-vase) versus a solid implant using a dual-material 3D-printed mandibular model and strain gauges. A 100 N static load was applied. Under eccentric loading, the solid implant generated extremely high tensile strain (871.67 µε), while porous designs reduced peak strains. The Hex-vase design transmitted the highest compressive strain (-795.85 µε), 65% greater in magnitude than the solid, suggesting improved mechanical stimulus transfer to peri-implant bone. The QDC design provided a moderate environment, suitable for compromised bone. Porous implants are biomechanically superior, offering customizable solutions to mitigate stress shielding.
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This study was supported by academic and government organizations: China Medical University (CMU113-MF-65) and National Science and Technology Council (NSTC 113-2221-E-039 -002 -MY3) in Taiwan.
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The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Institutional Review Board of China Medical University Hospital (protocol code: CMUH110-REC2-247).
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Zhang, H., Hsu, JT., Fuh, LJ. et al. Biomechanical evaluation of 3D-printed porous lattice versus solid mandibular implants: an in vitro study. Sci Rep (2026). https://doi.org/10.1038/s41598-026-50741-6
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DOI: https://doi.org/10.1038/s41598-026-50741-6


