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A modified four-zone classification of the posterior lumbar spinal canal: An anatomical study and clinical application in microchannel surgery
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  • Published: 13 May 2026

A modified four-zone classification of the posterior lumbar spinal canal: An anatomical study and clinical application in microchannel surgery

  • Longfei Shu1 na1,
  • Jianwei Zhuo2 na1,
  • Feihu Dai1 na1,
  • Xiaoming Li1,
  • Yan Liu3,
  • Dekang Nie4,
  • Jing Zhang5,
  • Chunmei Chen6,
  • Yuhai Wang1,
  • Qingchun Mu7 &
  • …
  • Wei Zhao1 

Scientific Reports (2026) Cite this article

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We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Anatomy
  • Diseases
  • Health care
  • Medical research

Abstract

This study introduces and evaluates a modified four-zone classification of the posterior lumbar spinal canal, assessing its anatomical basis and clinical utility in guiding microchannel surgery. Current minimally invasive lumbar procedures rely predominantly on fluoroscopic imaging of bony landmarks for localization, often neglecting the consistent anatomical boundaries provided by the ligamentum flavum for surgical orientation and trajectory planning. Anatomical measurements were performed on six fresh-frozen human cadaveric spines to define key parameters of the ligamentum flavum and their spatial relationships with adjacent structures. A retrospective clinical analysis compared 223 patients undergoing microchannel surgery: 103 patients in the conventional localization group (Group A) and 120 patients in the modified four-zone classification group (Group B). Outcomes assessed included fluoroscopy time, microchannel tilt angle, estimated blood loss, operative duration, length of hospital stay, VAS scores, ODI, and Modified MacNab criteria. Anatomically, the interligamentum flavum space measured 12.3 ± 1.8 mm on the left and 11.9 ± 1.9 mm on the right, with the S-point located approximately midway between the ligamentum flavum boundaries. Clinically, Group B demonstrated significant reductions in fluoroscopy time (4.4 ± 1.4 vs. 5.7 ± 1.7 min, p < 0.01), microchannel tilt angle (7.8 ± 2.7° vs. 10.1 ± 3.6°, p < 0.01), blood loss (44.7 ± 12.7 vs. 58.5 ± 13.5 ml, p < 0.01), operative time (69.4 ± 22.5 vs. 81.4 ± 27.1 min, p < 0.01), along with less early postoperative incision pain and length of hospital stay (p < 0.01). While long-term improvements in back pain VAS and ODI scores were similar between groups, Group B demonstrated superior outcomes in both leg pain VAS scores (final score: 0.5 ± 0.6 vs. 1.8 ± 0.8, p < 0.01) and patient satisfaction (Modified MacNab Excellent/Good rate: 85.8% vs. 75.7%, p = 0.03).The modified four-zone classification offers an anatomically reliable framework for posterior lumbar microchannel surgery, enabling precise anatomical targeting, reducing radiation exposure, and improving both perioperative and long-term functional outcomes, This approach may facilitate the standardization and enhancement of procedural precision.

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Abbreviations

LDH:

Lumbar disc herniation

LF:

Ligamentum flavum

inter-LF:

The interligamentum flavum space

sup-LF:

The superior boundary of the ligamentum flavum

inf-LF:

The inferior boundary of the ligamentum flavum

PLS:

Posterior lumbar spinal canal

VAS:

Visual analogue scale

ODI:

Oswestry disability index

Funding

This research was funded by Wuxi Health Commission Fund, grant number Q202363; Medical Independent Research Project of Joint Logistics Support Force Fund, grant number XK20240103; National Natural Science Foundation of China, grant number 81974453; and China Postdoctoral Science Foundation, grant number 2025M772173.

Author information

Author notes
  1. Longfei Shu, Jianwei Zhuo and Feihu Dai contributed equally to this work.

Authors and Affiliations

  1. Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force of PLA, Wuxi, 214044, China

    Longfei Shu, Feihu Dai, Xiaoming Li, Yuhai Wang & Wei Zhao

  2. Department of Neurosurgery, Taizhou Fourth People’s Hospital, Taizhou, 225300, China

    Jianwei Zhuo

  3. Department of Orthopedics, Jingjiang Chinese Medicine Hospital, Taizhou, 214500, China

    Yan Liu

  4. Dpartment of Neurosurgery, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, Yancheng, 224001, China

    Dekang Nie

  5. Department of Anatomy, Mudanjiang Medical University, Mudanjiang, 157011, China

    Jing Zhang

  6. Department of Neurosurgery, The Second Affiliated Hospital of of Fujian Traditional Chinese Medicine University, Fuzhou, 350003, China

    Chunmei Chen

  7. Department of Neurosurgery, Second Affiliated Hospital of Soochow University, Suzhou, 215004, China

    Qingchun Mu

Authors
  1. Longfei Shu
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  2. Jianwei Zhuo
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  4. Xiaoming Li
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  5. Yan Liu
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  6. Dekang Nie
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  7. Jing Zhang
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  8. Chunmei Chen
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  9. Yuhai Wang
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  10. Qingchun Mu
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  11. Wei Zhao
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Corresponding authors

Correspondence to Qingchun Mu or Wei Zhao.

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The authors declare no competing interests.

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Cite this article

Shu, L., Zhuo, J., Dai, F. et al. A modified four-zone classification of the posterior lumbar spinal canal: An anatomical study and clinical application in microchannel surgery. Sci Rep (2026). https://doi.org/10.1038/s41598-026-53026-0

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  • Received: 12 December 2025

  • Accepted: 11 May 2026

  • Published: 13 May 2026

  • DOI: https://doi.org/10.1038/s41598-026-53026-0

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Keywords

  • Microdiscectomy
  • Microscopy
  • Landmark༛Ligamentum flavum
  • Lumbar disc herniation
  • Interlaminar approach
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