Table 2 Parallels within models of biological and behavioral immune systems.

From: An adaptive behavioral immune system: a model of population health behavior

General function

General responsibility

Specific functions

Definition of specific function

Evidence in the biological immune system

Evidence in the adaptive behavioral immune system

Precision

The functions that prioritize and organize rhythms or variations that sustain health in future environments

Detection

The cost-benefit analyses that set a point of reference from which to reliably change functioning

Detection and pattern recognition functions performed by toll-like receptors

The weighting of pros/cons in TTM’s Decisional Balance

Direction

The sequencing of events within the system that support movement (from a detected point of reference) towards a future state of healthy functioning

A coordination of immune events following the detection of an antigen; A coordination of immune events following the detection of self-antigens in autoimmune patients;

The sequencing of behavior change events to create movement through TTM’s five Stages of Change

Selection

The conditioning of precise responses that readily replace dysfunctional conditions with functional conditions (to maintain direction).

The functioning of enzymes and antibodies to tag, neutralize, and remove pathogens

The use of TTM’s Processes of Change to tag, neutralize, and replace bad habits

Variation

The functions that express the “varied-abilities” that evidence health in presently changing environment

(to be addressed

in future work)

The human microbiota: the systemic colonies of microorganisms that continuously vary to sustain life of the biological tissue

Breathing, drinking, eating, and moving: the habitual life functions that continuously vary to sustain life in the human body