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Effectiveness and Consistency of Occupational Health Safety Programs

Lab Animal volume 51, pages 149–150 (2022)Cite this article

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Several concerns jump out quickly, and several trigger the need for clarification which may serve to launch discussions to improve the culture of safety associated with approved animal procedures.

First, tamoxifen is classified as a hazardous drug and a known human carcinogen, teratogen, and mutagen according to the National Institute for Occupational Safety and Health. The GEU’s IACUC response indicated they take mishandling of tamoxifen seriously. Personal protective equipment (PPE) recommended for handling tamoxifen and injected animals include non-permeable gloves, often double, and long sleeve coats, safety glasses, and respiratory protection depending on the presence of aerosol production. GEU further required containment housing following administration.

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References

  1. Office of Laboratory Animal Welfare, National Institutes of Health. Building a Research Occupational Health Program. https://olaw.nih.gov/education/educational-resources/webinar-2020-03-12.htm

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Authors and Affiliations

  1. The University of Michigan, Ann Arbor, Michigan, USA

    Karl J. Jepsen, Janet Follo, Danielle Sheen & Kevin Ferrell

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  1. Karl J. Jepsen
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  2. Janet Follo
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  3. Danielle Sheen
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  4. Kevin Ferrell
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Correspondence to Karl J. Jepsen.

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Jepsen, K.J., Follo, J., Sheen, D. et al. Effectiveness and Consistency of Occupational Health Safety Programs. Lab Anim 51, 149–150 (2022). https://doi.org/10.1038/s41684-022-00984-3

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  • DOI: https://doi.org/10.1038/s41684-022-00984-3

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