Extended Data Fig. 1: The effect of SI on mouse locomotion, exploration, spatial working memory, anxiety-like behaviors, and fear memory.
From: Early growth response 2 in the mPFC regulates mouse social and cooperative behaviors
Postnatal day 21 mice were housed singly or in groups for 3 weeks before the behavioral tests. a, Locomotion, and exploration behavior of GH and SI mice at P56 in the open field. b, The spatial working memory performance of P57 GH and SI mice in the Y-maze testing. c, The anxiety-like behavior of P58 GH and SI mice examined by the elevated plus-maze test. d, Fear memory performance of GH and SI mice at P58-59 in the fear conditioning test. Data are represented as medians and IQR (n = 18 in each group). Data were analyzed by two-tailed Student’s t-tests. GH: group housing; SI: social isolation.
