Fig. 1: WU23 tissue tropism mirrors acute MNV1 tropism in adult mice. | Lab Animal

Fig. 1: WU23 tissue tropism mirrors acute MNV1 tropism in adult mice.

From: Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis

Fig. 1

a–e, Groups of adult C57BL/6J (B6) mice were p.o. infected with 107 TCID50 units of WU23, MNV1 or CR6. At 1 (n = 6 per condition) or 2 (n = 7–10 per condition) dpi, viral titers were determined in the duodenum (a), ileum (b), colon (c), spleen (d) and liver (e) by plaque assay (pfu, plaque forming unit). Data are presented as mean ± s.e.m.; P values were determined using two-sided ANOVA with corrections for multiple comparisons using Tukey’s test. *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001. Dashed line indicates limit of detection (LD).

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