Fig. 1: PMV constructs and study design. | Lab Animal

Fig. 1: PMV constructs and study design.

From: Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

Fig. 1: PMV constructs and study design.

a, Illustration of the three PMV constructs of VAR2CSA used in this study. Boundaries of each construct are shown as amino acid residues from the corresponding VAR2CSA allele (FCR3 and 3D7) and M1010 composite sequence. b, Flow chart of the study, highlighting the different stages of the study and the number of animals involved in each stage. Timeline indicates three vaccinations (Vac1, Vac2 and Vac3) with PMV and Pfs25 antigens. ATS, acid terminal sequence; cVLP, capsid-based virus like particle; EPA, mutagenized Pseudomonas aeruginosa exoprotein A; TM, transmembrane.

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