Fig. 3: Correlations between ELISA titers of PMV-induced antibodies and functional activity at D70 post-vaccination. | Lab Animal

Fig. 3: Correlations between ELISA titers of PMV-induced antibodies and functional activity at D70 post-vaccination.

From: Aotus nancymaae model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

Fig. 3: Correlations between ELISA titers of PMV-induced antibodies and functional activity at D70 post-vaccination.

a–c, Spearman (ρ) coefficients and P values are reported to describe the relationship between ELISA titers of PAMVAC antibodies in Aotus (n = 9) and surface reactivity (a) or binding inhibition activity (b) against CS2 parasite. The correlation between surface reactivity and BIA of PAMVAC antibodies is also shown (c). d–f, The same analyses were performed for PRIMVAC-induced antibodies in Aotus (n = 9). Data for animals immunized with PAMVAC (blue circle) and PRIMVAC (open red square) are shown.

Source data

Back to article page