Fig. 1: Experimental setup.
From: Meta-inflammation and endotoxemia in a highly translational porcine model of diet-induced obesity

Twenty-six Göttingen minipigs were divided into two equal groups and fed either the HFFC diet (n = 13) or the SD diet (n = 13) for 103 days. Blood samples were collected from all animals throughout the study. CRP concentrations were quantified on days 0, 20, 41, 62, 83 and 98. Lipid concentrations were quantified on days 0, 62, 83 and 98. White blood cell counts were performed on days 0 and 98. LPS concentrations were quantified on day 99. Gene expression in circulating leukocytes was quantified on days 0, 20, 41, 62, 83 and 98. Gene expression in liver tissue and VAT was quantified in four randomly selected pigs from each diet group on day 103. Created in BioRender. Henriksen, B. (2025) https://BioRender.com/25rsuz8.