Fig. 4: Impact of alternative humane endpoints on time in study.
From: Exploration of refined humane endpoints for melioidosis in BALB/c mice
a,b, ‘Median days saved’ per mouse across humane endpoints derived according to weight loss threshold (x axes) and clinical sign threshold (blue/green color), using ‘total signs’ metric (a), or ‘average total signs’ metric (b) (data from all four studies used; n = 556 mice). The error bars represent the 95% CIs for the ‘median days saved’.
