Fig. 2: The link between MMR and HRR. | npj Precision Oncology

Fig. 2: The link between MMR and HRR.

From: The intersection of homologous recombination (HR) and mismatch repair (MMR) pathways in DNA repair-defective tumors

Fig. 2

Emerging studies highlight potential interactions of mechanisms that underly different forms of DNA repair, such as MMR and HRR. Shared core proteins, including RPA, EXO1, RFC, MSH2/3, MLH3, and PMS2, are identified as key players in both pathways, broadening the concept of DNA repair mechanism exclusivity in specific tumor types (Created with BioRender.com).

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