Fig. 1: Features of BRAF-mutant appendiceal adenocarcinoma (AA) and colorectal cancer (CRC). | npj Precision Oncology

Fig. 1: Features of BRAF-mutant appendiceal adenocarcinoma (AA) and colorectal cancer (CRC).

From: BRAF mutant appendiceal adenocarcinoma differs from colorectal cancer but responds to BRAF-targeted therapy

Fig. 1: Features of BRAF-mutant appendiceal adenocarcinoma (AA) and colorectal cancer (CRC).The alternative text for this image may have been generated using AI.

A Variant proportions in BRAF mutant AA and CRC sorted by BRAF mutation class. B Proportions of BRAF mutation in AA and CRC split by BRAF mutation class. C Comparison of patient sex in BRAFWT (gray) vs. BRAFV600E (blue) vs. aBRAF (skyblue) AA and CRC. D Comparison of proportion of mucinous tumors (mucinous adenocarcinoma and mucinous features) in BRAFWT (gray) vs. BRAFV600E (blue) vs. aBRAF (skyblue) AA and CRC. E Comparison of high-level microsatellite instability in BRAFWT (gray) vs. BRAFV600E (blue) vs. aBRAF (skyblue) AA and CRC. F Comparison of poor differentiation (grade 3+) in BRAFWT (gray) vs. BRAFV600E (blue) vs. aBRAF (skyblue) AA and CRC. P-value by Pearson’s Chi-Squared. *, <0.05; **, <0.01; ***, <0.001; ****, <0.0001. No comparison shown within cancers = not significant.

Back to article page