Table 4 Clinical characteristics of non-component cancers with elevated SIRs

From: Extended spectrum of cancers in PTEN hamartoma tumor syndrome

Participant

Sex

Age at consent

Cancer type

Histology

Age at diagnosis

2094-01-002

Female

58

Ovarian cancer

Endometrioid adenocarcinoma

36

2736-01-001

Female

63

Ovarian cancer

Serous carcinoma, poorly differentiated

62

12794-01-001

Female

51

Ovarian cancer

Serous carcinoma, poorly differentiated

49

18411-01-001

Female

79

Ovarian cancer

Malignant neoplasm of ovary, NOS

31

2854-01-001

Female

53

Ovarian cancer

Endometrioid adenocarcinoma, well-differentiateda

52

7232-01-001

Female

59

Ovarian cancer

Endometrioid adenocarcinoma with squamous metaplasiaa

46

9310-01-001

Female

60

Ovarian cancer

Endometrioid adenocarcinoma, moderately-differentiated

59

10299-01-001

Female

49

Ovarian cancer

Malignant neoplasm of ovary, NOS

48

11498-01-001

Female

51

Ovarian cancer

Adult granulosa cell tumor

46

12856-01-001

Female

63

Ovarian cancer

Malignant neoplasm of ovary, NOS

61

1027-01-001

Male

73

Prostate cancer

No information available

Not reported

1140-01-001

Male

59

Prostate cancer

Adenocarcinoma, Gleason score 7

60

1679-01-001

Male

67

Prostate cancer

No information available

Not reported

8969-01-001

Male

50

Prostate cancer

Adenocarcinoma, Gleason score 7

45

9346-01-001

Male

59

Prostate cancer

No information available

59

37-01-001

Male

73

Prostate cancer

No information available

72

1824-01-002

Male

62

Prostate cancer

Adenocarcinoma, Gleason score 6

59

3935-01-001

Male

45

Prostate cancer

Adenocarcinoma, Gleason score 7

57

5953-01-001

Male

65

Prostate cancer

Adenocarcinoma, Gleason score 7

62

14797-01-001

Male

60

Prostate cancer

Adenocarcinoma, Gleason score 8

54

5953-01-001

Male

65

Soft tissue

Malignant giant cell tumor of tendon sheath, right hand

46

Chondrosarcoma

59

8146-02-002

Male

47

Soft tissue

Cutaneous leiomyosarcoma, forehead

47

8144-01-001

Female

47

Soft tissue

Cutaneous leiomyosarcoma

42

559-01-001

Female

39

Soft tissue

Ewing sarcoma

46

3504-01-001

Female

56

Soft tissue

Liposarcoma

Not reported

9639-01-001

Female

55

Soft tissue

Osteosarcoma

13

12150-01-001

Female

3

Soft tissue

Brain Kaposiform hemangioendothelioma

4

  1. aCases with synchronous primary tumors in both the ovaries and the endometrium
  2. SIR, standardized incidence ratio; NOS, not otherwise specified.