Fig. 3: The figure compares the primary tumorigenic characteristics of left-sided and right-sided colorectal cancer, highlighting distinct molecular features that differentiate these subtypes.
Understanding these differences is crucial, as they can influence the development of tailored therapeutic strategies. For instance, variations in genetic mutations, signaling pathways, and tumor microenvironments may affect treatment responses and prognoses, underscoring the need for personalized approaches in managing colorectal cancer effectively. CRC colorectal cancer, MSI microsatellite instability, TMB tumor mutational burden.
