Fig. 2: Characterization of immune cell populations during cervical cancer progression. | npj Precision Oncology

Fig. 2: Characterization of immune cell populations during cervical cancer progression.

From: Deciphering the cellular and molecular landscape of cervical cancer progression through single-cell and spatial transcriptomics

Fig. 2

A UMAP visualization of T cell subclusters, colored by cell type, showing distinct populations of CD4 + T cells (exhausted PDCD1 + , exhausted CTLA4 + , and naive), CD8 + T cells (GZMB+ and GZMK+ CTLs), and Th17 cells. B Dot plot showing expression of signature genes across T cell subclusters. C Stacked bar chart depicting the proportion of T cell subclusters across different disease stages. D UMAP visualization of B cell subclusters, colored by cell type. E Dot plot showing expression of signature genes across B cell subclusters. F Stacked bar chart depicting the proportion of B cell subclusters across different disease stages. G Heatmap showing the tissue distribution preference of B cell subclusters across different disease stages. H Feature plots showing expression of representative neutrophil markers (CSF3R, FCGR3B, NAMPT). I UMAP visualization of neutrophil subclusters, colored by cell type. J Stacked bar chart depicting the proportion of neutrophil subclusters across different disease stages. K Heatmap showing the tissue distribution preference of neutrophil subclusters across different disease stages.

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