Fig. 3: LHX1-DT inhibits RCC cell proliferation and metastasis in vitro and in vivo. | npj Precision Oncology

Fig. 3: LHX1-DT inhibits RCC cell proliferation and metastasis in vitro and in vivo.

From: m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p

Fig. 3

A, B Verification of LHX1-DT overexpression (A) and knockdown (B) by qRT-PCR. C, D Cell proliferation assay of 786-O and Caki-1 cells transfected with functional LHX1-DT-cDNA (C) and LHX1-DT-shRNA (D). E, F Cell invasion assay of 786-O and Caki-1 cells transfected with functional LHX1-DT-cDNA (E) and LHX1-DT-shRNA (F). G Tumors collected from nude mice are exhibited. H, I Tumor volume (H) and weight (I) were dramatically decreased in LHX1-DT overexpression group. J Representative images of IHC staining of Ki-67 from the tumor sections. K LHX1-DT expression in tumors detected by qRT-PCR.

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