Fig. 3: Concordance between oral rinse-derived cfDNA, plasma cfDNA, and tumour gDNA genotyping. | npj Precision Oncology

Fig. 3: Concordance between oral rinse-derived cfDNA, plasma cfDNA, and tumour gDNA genotyping.

From: Integrated analysis of oral rinse-derived and plasma circulating tumour DNA for mutation profiling and outcome prediction with oral squamous cell carcinoma

Fig. 3

A–C Venn diagrams showing the number of mutations in oral rinse-derived cfDNA and tumour gDNA (A), plasma cfDNA and tumour gDNA (B), and those shared between tissue and oral rinse-derived or plasma cfDNA (C). D Bar graph showing the allele frequency of variants in tumour gDNA. Blue bars indicate mutations detected in both tumour gDNA and cfDNA (oral rinse-derived or plasma), while red bars show mutations detected only in tumour gDNA. E Correlation between tumour DNA content in oral rinse and plasma samples. cfDNA cell-free DNA, gDNA genomic DNA.

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