Fig. 1: Identification of putative target genes and regulatory pathways for miR-605-3p in GBM.
From: Deciphering the YY1/ lncRNA BLACAT1/miR-605-3p axis in glioblastoma: implications for therapy
A Volcano plot illustrates the selection of target genes identified through TargetScan 7.2. Red dots indicate upregulated genes, blue dots indicate downregulated genes, and gray dots indicate non-DEGs. B Survival analysis results for the selected genes, based on OS, PFS, and DSS, with significance set at P < 0.05 and a hazard ratio (HR_categorical) >1.5. C Predicted regulatory pathways showing the potential mechanisms governing the YY1/lncRNA BLACAT1/miR-605-3p axis in glioblastoma. D Results of GO analysis. E Results of KEGG analysis. F Survival curves. G Time-dependent ROC curves. H Immune landscape analysis. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Each experiment was performed with three independent biological replicates.
