Fig. 4: Functional validation of YY1 and miR-605-3p in glioblastoma metastasis and vascular formation. | npj Precision Oncology

Fig. 4: Functional validation of YY1 and miR-605-3p in glioblastoma metastasis and vascular formation.

From: Deciphering the YY1/ lncRNA BLACAT1/miR-605-3p axis in glioblastoma: implications for therapy

Fig. 4

A Scratch assay results showing the effects of YY1 knockout and miR-605-3p mimic transfection on glioblastoma cell migration. B Invasion assay outcomes demonstrating changes in glioblastoma cell invasion following YY1 knockout and miR-605-3p mimic transfection. C Clonogenic assay results illustrating differences in colony formation among the experimental groups. D Vascular formation assay observations highlighting the impact of YY1 knockout on vascular formation using HuvEC cells. ns p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Each experiment was performed with three independent biological replicates.

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