Table 1 Patient Clinicopathologic Characteristics
From: Multi-omic characterization of early-onset esophagogastric cancer
EOEGC | IOEGC | AOEGC | |||
|---|---|---|---|---|---|
Count (N) | 530 | 1744 | 2901 | ||
Median Age [range] | 43 [14–49] | 59 [50–64] | 73 [65–>89] | ||
Sex | Male | 66.0% (350/530) | 74.9% (1306/1744) | 73.7% (2139/2901) | |
Female | 34.0% (180/530) | 25.1% (438/1744) | 26.3% (762/2901) | ||
Lineage | Esophagogastric Junction Carcinoma | 39.4% (209/530) | 50.8% (886/1744) | 50.7% (1470/2901) | |
Gastric Adenocarcinoma | 53.4% (283/530) | 34.8% (607/1744) | 33.6% (974/2901) | ||
Esophageal Carcinoma | 7.2% (38/530) | 14.4% (251/1744) | 15.7% (457/2901) | ||
Histology | Adenocarcinoma | 76.4% (405/530) | 74.8% (1304/1744) | 75.8% (2198/2901) | |
Squamous | 4.5% (24/530) | 10.8% (188/1744) | 12.4% (359/2901) | ||
Other/mixed | 19.1% (101/530) | 14.4% (252/1744) | 11.8% (344/2901) | ||
Lauren subtype | Diffuse | 12.8% (68/530) | 6.1% (107/1744) | 5.3% (153/2901) | |
Intestinal | 0.6% (3/530) | 0.9% (16/1744) | 1.4% (42/2901) | ||
Mixed/unclear | 86.6% (459/530) | 93% (1621/1744) | 93.3% (2706/2901) | ||
Specimen site | Primary | 60.6% (321/530) | 65.5% (1162/1744) | 75.7% (2197/2901) | |
Metastatic | Liver | 4.3% (23/530) | 4.2% (74/1744) | 3.3% (96/2901) | |
Peritoneum/Retroperitoneum | 7.5% (40/530) | 7.4% (129/1744) | 6.7% (195/2901) | ||
Lymph Node | 5.3% (28/530) | 4.8% (84/1744) | 3.4% (99/2901) | ||
Other | 22.3% (118/530) | 16.9% (295/1744) | 10.8% (314/2901) | ||
Smoking History | Yes | 94.6% (52/55) | 94.4% (303/321) | 95.5% (429/449) | |
No | 5.5% (3/55) | 5.6% (18/321) | 4.5% (20/449) | ||
Race | White | 64.2% (174/271) | 69.5% (763/1098) | 78.8% (2009/2551) | |
Black | 19.2% (52/271) | 16.6% (182/1098) | 11.3% (289/2551) | ||
Asian/Pacific Islander | 8.1% (22/271) | 6.6% (73/1098) | 5.2% (132/2551) | ||
Other | 8.5% (23/271) | 7.3% (80/1098) | 4.7% (121/2551) | ||
Ethnicity | Not Hispanic or Latino | 72.5% (195/269) | 82.3% (919/1116) | 87.9% (2231/2537) | |
Hispanic or Latino | 27.5% (74/269) | 17.7% (197/1116) | 12.1% (306/2537) | ||