Table 1 Predicting the specific structural domains of CRABP2 and FABP5 mRNA binding to METTL3 and ALKBH5 proteins using the catRAPID database

From: ZEB1 and ALKBH5 coregulate CRABP2 and FABP5 and jointly determine the sensitivity of anaplastic thyroid cancers to gemcitabine and retinoic acid

Protein Region

mRNA Region

Interaction Propensity

Normalized Score

METTL3

170–221

CRABP2

201–252

23.57

4.30

170–221

205–256

22.97

4.19

345–396

201–252

13.89

2.63

345–396

205–256

13.56

2.57

51–102

FABP5

108–159

13.53

3.38

51–102

83–134

9.05

2.63

55–106

108–159

6.74

2.24

101–152

108–159

5.00

1.94

ALKBH5

26–77

CRABP2

276–327

9.11

2.52

26–77

51–102

8.78

2.44

169–220

276–327

7.97

2.21

169–220

51–102

7.70

2.15

44–95

FABP5

108–159

4.52

2.20

51–102

108–159

4.15

2.13

44–95

134–184

2.25

1.77

51–102

134–184

2.24

1.77

METTL3 Protein

ALKBH5 Protein

CRABP2 mRNA

FABP5 mRNA

P#1 51–106

P#1 26–77

R#1 51–102

R#1 83–134

P#2 101–152

P#2 44–95

R#2 201–256

R#2 108–159

P#3 170–221

P#3 51–102

R#3 276–327

R#3 133–184

P#4 345–396

P#4 169–220

  
  1. The detailed computational method for determining both the Interaction Propensity and Normalized Score is comprehensively documented within the catRAPID database (http://service.tartaglialab.com/page/catrapid_group).
Back to article page