Table 2 DNA methylation scores and methylation classes of primary tumors and PDT based on the online classifier (https://app.epignostix.com)
Tumor ID | Tumor diagnosis | DNA methylation score | Methylation class |
|---|---|---|---|
HGG_02 | Pediatric-type diffuse high-grade gliomas | 0.96 | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype |
PDT | 0.84 | Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype | |
HGG_04 | Infant-type hemispheric glioma | 0.93 | Infant-type hemispheric glioma |
PDT | 0.99 | Infant-type hemispheric glioma | |
MB_01 | Group 4 medulloblastoma | 0.99 | Medulloblastoma, Non Wnt/non Shh, Group 4 Subtype, Subclass Vii |
PDO | 0.99 | Medulloblastoma, Non Wnt/non Shh, Group 4 Subtype, Subclass Vii | |
MB_02 | Group 4 medulloblastoma | 0.99 | Medulloblastoma, Non Wnt/non Shh, Group 4 Subtype, Subclass Viii |
PDO | 0.99 | Medulloblastoma, Non Wnt/non Shh, Group 4 Subtype, Subclass Viii | |
MB_03 | Group 4 medulloblastoma | 0.82 | Medulloblastoma, non-WNT/non-SHH (score 0.98), Group 4 subtype (score 0.82) |
PDO | 0.58 | Medulloblastoma, non-WNT/non-SHH (score 0.98), Group 4 subtype (score 0.58) | |
ATRT | Atypical theratoid rhadoid tumor | 0.99 | Atypical Teratoid/rhabdoid Tumor |
PDO | 0.99 | Atypical Teratoid/rhabdoid Tumor | |
MNG | Meningioma | 0.99 | Meningioma, Subtype Benign, Subclass 3 |
PDO | 0.99 | Meningioma, Subtype Benign, Subclass 3 |
