Table 1 Baseline patient characteristics

From: A signal-seeking phase 2 study of tremelimumab in advanced cancers with high tumour mutational burden

Characteristic

Number (N = 21)

%

Median age, years (range)

66 (38–82)

Male sex

12

57.1%

ECOG performance status

 0

5

23.8%

 1

14

66.7%

 2

2

9.5%

Lines of prior systemic treatment, median (range)

3 (1–7)

Cancer types

1. Sarcoma

4

19.0%

 Angiosarcoma (scalp/nasal cavity)

2

9.5%

 Pleomorphic sarcoma

2

9.5%

2. Carcinoma

16

76.2%

 Atypical pituitary adenoma

1

4.8%

 Primary adenocarcinoma of bladder

1

4.8%

 Breast adenocarcinoma

1

4.8%

 Colorectal adenocarcinoma

5

23.8%

 Cholangiocarcinoma

2

9.5%

 Carcinoma of unknown primary

1

4.8%

 Endometrial adenocarcinoma

1

4.8%

 Oesophageal squamous cell carcinoma

1

4.8%

 Small intestine adenocarcinoma

1

4.8%

 Thyroid carcinoma

1

4.8%

 High-grade serous ovarian cancer

1

4.8%

3. Other (oligodendroglioma)

1

4.8%