Table 2 Statistically significant comparisons of PB rare cells between disease states

From: Characterizing circulating rare cells in peripheral blood for detecting and monitoring multiple myeloma and precursor states

Groups (1 vs. 2)

Event Type

P-value

Mean 1

Mean 2

MGUS vs. NDMM

D | 138 | BCMA-Memb

0.0021

1.0026

3.4532

D | 138

0.0081

0.1888

1.8354

Total Cells

0.0150

4.3766

5.7071

D | BCMA-Memb|45

0.0169

1.5441

3.0236

Total BCMA-Memb Cells

0.0169

3.5482

4.9519

Total BCMA+ Cells

0.0190

4.1197

5.5063

Total 138+ Cells

0.0409

3.4876

4.8627

MGUS vs. SMM

D | 138 | BCMA-Memb

0.0044

1.0026

2.7346

NDMM vs. RRMM

D | BCMA-Peri|45

0.0036

0.9558

0.4274

Total BCMA-Peri Cells

0.0043

4.1966

2.2193

D | BCMA-Memb|45

0.0324

3.0236

1.8540

MGUS vs. RRMM

D | 138 | BCMA-Memb

0.0038

1.0026

3.6084

D | 138

0.0084

0.1888

2.3244

SMM vs. NDMM

D | BCMA-Peri|45

0.0190

2.7677

4.1726

D | BCMA-Memb|45

0.0229

1.8338

3.0236

Total BCMA-Peri Cells

0.0294

2.9458

4.9519

  1. D DAPI, 138: CD138, 45: CD45, Peri perinuclear localization of BCMA, Memb membrane bound BCMA. Two-sided Wilcoxon rank sum test with significance determined at a P-value < 0.05.
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