Fig. 1: Identification of differentially expressed genes (DERs) at the DNA methylation and mRNA levels.

A Differentially expressed genes at the DNA methylation level in the GSE120288 dataset. B Differentially expressed genes at the DNA methylation level in the TCGA-BLCA dataset. C Differentially expressed genes at the mRNA level in the TCGA-BLCA dataset. D, E Common differentially expressed genes at the DNA methylation level across tissue, blood, and urine samples. F Methylation-related genes (MRGs) identified by the intersection of all differentially expressed genes at both the DNA methylation and mRNA levels.