Fig. 5: Histopathological differences between LNM-positive and LNM-negative groups based on UNI_CTMIL model predictions (150 patches per group).

A representative tumor patches from LNM-positive (left) and LNM-negative (right) groups, selected based on combinations of high attention with high or low classification scores. B bar plots showing the number of patches exhibiting each histopathological feature. C radar plot showing the proportion of patches positive for each microenvironmental component. D Sankey diagram illustrating co-occurrence patterns of key histopathological features in the two groups. nLNM, LNM-negative. None (not evaluable), insufficient tumor cells or representative architecture within a patch to assess growth pattern or differentiation. *, P < 0.05; **, P < 0.01; ***, P < 0.001.