Table 1 Baseline characteristics of the patients

From: Disitamab vedotin (RC48-ADC) combined with immunotherapy as neoadjuvant therapy for localized muscle-invasive bladder cancer: a multicenter real-world study

Characteristics

Values (%)

Median age (range), years

69 (46–79)

Sex, n (%)

 Male

21 (84.0)

 Female

4 (16.0)

Eastern Cooperative Oncology Group performance status, n (%)

 0

23 (92.0)

 1

2 (8.0)

Smoking, n (%)

 Yes

6 (24.0)

 No

19 (76.0)

Treatment regimens, n (%)

 RC48 + Toripalimab

13 (52.0)

 RC48 + Tislelizumab

9 (36.0)

 RC48 + Pembrolizumab

3 (12.0)

 Treatment cycles (range)

5 (4–7)

T stage, n (%)

 T2

18 (72.0)

 T3

5 (20.0)

 T4

2 (8.0)

N stage, n (%)

 N0

18 (72.0)

 N1

5 (20.0)

 N2

2 (8.0)

Baseline Pathological Typea, n (%)

 Conventional UC

16 (64.0)

 UC with squamous differentiation

4 (16.0)

 Sarcomatoid UC

5 (20.0)

HER2 status, n (%)

 IHC 0

1 (4.0)

 IHC 1+

1 (4.0)

 IHC 2+

10 (40.0)

 IHC 3+

13 (52.0)

  1. HER2 human epidermal growth factor receptor 2, IHC immunohistochemistry, UC urothelial carcinoma, WHO World Health Organization.
  2. aAccording to the 2022 WHO Classification of Urinary and Male Genital Tumors (5th Edition).