Table 1 Baseline patient characteristics
Characteristic | Training set (n = 162) | External vali-set 1 (n = 74) | External vali-set 2 (n = 30) | p value |
|---|---|---|---|---|
Age (y)* | 58 (50–67) | 54 (45–63) | 58 (50–69) | 0.016 |
Gender (male) | 146 (90.1) | 66 (89.2) | 19 (63.3) | <0.001 |
Cirrhosis | 123 (75.9) | 21 (28.4) | NA | <0.001 |
AFP > 100 ng/ml | 46 (28.4) | 27 (36.5) | 8 (26.7) | 0.407 |
PLT > 100×109/L | 139 (85.8) | 62 (83.8) | 27 (90) | 0.713 |
ALT > 50 U/L | 31 (19.1) | 23 (31.1) | NA | 0.063 |
AST > 40 U/L | 53 (32.7) | 29 (39.2) | NA | 0.411 |
TBIL > 17.1 μmol/L | 54 (33.3) | 27 (36.5) | 5 (16.7) | 0.134 |
ALB > 40 g/L | 97 (59.9) | 35 (47.3) | 11 (36.7) | 0.027 |
mALBI | 0.068 | |||
1 | 107 (66) | 36 (48.6) | 16 (53.3) | |
2a | 34 (21) | 22 (29.7) | 6 (20) | |
2b | 21 (13) | 14 (18.9) | 7 (23.3) | |
3 | 0 (0) | 2 (2.7) | 1 (3.3) | |
PT > 13 s | 23 (14.2) | 20 (27) | 2 (6.7) | 0.014 |
LI-RADS category† | 0.315 | |||
LR-3 | 18 (11.1) | 9 (12.2) | 1 (3.3) | |
LR-4 | 38 (23.5) | 18 (24.3) | 5 (16.7) | |
LR-5 | 56 (34.6) | 32 (43.2) | 14 (46.7) | |
LR-M | 49 (30.2) | 13 (17.6) | 9 (30) | |
LR-TIV | 1 (0.6) | 2 (2.7) | 1 (3.3) | |
MTM subtype | 27 (16.7) | 22 (29.7) | 10 (33.3) | 0.024 |
VETC pattern | 52 (32.1) | 35 (47.3) | 6 (20) | 0.014 |
MTM-VETC positivity | 22 (13.6) | 21 (28.4) | 5 (16.7) | 0.023 |
