Table 2 Significantly shared loci between prostate cancer and testicular cancer according to colocalization analysis

From: Comprehensive genomic insights into the genetic causality and comorbidity in urological cancers

SNP

PP.H0

PP.H1

PP.H2

PP.H3

PP.H4

Gene

rs11774063

5.60E-54

0.02

8.47E-54

2.63E-02

0.96

NKX3-1

rs11135766

5.60E-54

0.02

8.49E-54

2.64E-02

0.96

NKX3-1

rs77102566

5.60E-54

0.02

8.49E-54

2.64E-02

0.96

NKX3-1

rs10448067

5.60E-54

0.02

8.49E-54

2.64E-02

0.96

NKX3-1

rs907587

5.60E-54

0.02

8.52E-54

2.65E-02

0.96

NKX3-1

rs7005539

5.60E-54

0.02

8.54E-54

2.65E-02

0.96

SLC25A37

rs10099421

5.60E-54

0.02

8.56E-54

2.66E-02

0.96

SLC25A37

  1. H0: no association with either trait.
  2. H1 and H2: association with only one of the traits.
  3. H3: association with both traits via distinct SNPs.
  4. H4: association with both traits via a shared SNP.
  5. PPH4 > 0.95 is the threshold for significant colocalization.
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