Fig. 1: RICH1 expression is associated with the types of tumor-infiltrating macrophages and prognosis in breast cancer. | npj Precision Oncology

Fig. 1: RICH1 expression is associated with the types of tumor-infiltrating macrophages and prognosis in breast cancer.

From: RICH1 enhances pro-inflammatory TAM infiltration in breast cancer via promoting TRIM21-mediated ubiquitination of RhoA and inhibiting STAT3 phosphorylation

Fig. 1: RICH1 expression is associated with the types of tumor-infiltrating macrophages and prognosis in breast cancer.

A RICH1-related KEGG pathways of NES top10 enriched by GSEA. B Violin plot of proportion of tumor-infiltrating immune cells compared in the samples with different expression of RICH1 obtained from TCGA database. C A meta-analysis conducted based on datasets GSE42568, GSE103091 and GSE31519. D The clusters using spatial transcriptomic UMAP analysis for the breast cancer sample (Block ID: 1168993F from the 10x Genomics Visium platform) with significant regional differences. E Spatial distribution of RICH1 expression, CD68+ and CXCL9+ labeled macrophages.

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