Fig. 5: Prediction of recurrence using an elastic net regression model approach.

a Overview of the design of the two elastic net regression models. b, c Variable importance plot of the 20 most important variables in the model with all data and without DNA data. cfDNA cell-free circulating DNA, ctDNA cell-free circulating tumor DNA, CVD Cerebrovascular disease, GP Gene program, HM Hallmarks of Cancer, NS NanoString.