Table 1 The upregulated pathways of MARCO+ macrophages in distinct cancer types
Pathway | Number of Cancer Types | Cancer Types |
|---|---|---|
EPITHELIAL_MESENCHYMAL_TRANSITION | 7 | PDAC, SKCM, STAD, COAD, NPC, GBM, PRAD |
HYPOXIA | 6 | PDAC, SKCM, STAD, NPC, GBM, PRAD |
GLYCOLYSIS | 6 | PDAC, SKCM, STAD, COAD, NPC, GBM |
ANGIOGENESIS | 5 | PDAC, SKCM, NPC, GBM, CHOL |
COMPLEMENT | 5 | PDAC, SKCM, NPC, GBM, PRAD |
ACUTE_INFLAMMATORY_RESPONSE | 5 | SKCM, STAD, NPC, ESCA, PRAD |
KRAS_SIGNALING_UP | 4 | SKCM, COAD, NPC, PRAD |
XENOBIOTIC_METABOLISM | 4 | PDAC, COAD, NPC, LUAD |
MTORC1_SIGNALING | 4 | PDAC, STAD, GBM, PRAD |
TNFA_SIGNALING_VIA_NFKB | 4 | SKCM, NPC, GBM, PRAD |
INFLAMMATORY_RESPONSE | 4 | SKCM, NPC, GBM, PRAD |
ACUTE_PHASE_RESPONSE | 4 | SKCM, COAD, NPC, PRAD |
CHOLESTEROL_HOMEOSTASIS | 4 | PDAC, LUAD, ESCA, PRAD |
ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE | 4 | SKCM, NPC, CHOL, KIRC |
ADP_METABOLIC_PROCESS | 3 | SKCM, STAD, GBM |
INTERFERON_GAMMA_RESPONSE | 3 | PDAC, NPC, PRAD |
IL2_STAT5_SIGNALING | 3 | PDAC, GBM, PRAD |
APOPTOSIS | 3 | SKCM, NPC, PRAD |
UV_RESPONSE_UP | 3 | SKCM, NPC, PRAD |
AMYLOID_BETA_CLEARANCE | 3 | STAD, ESCA, KIRC |
P53_PATHWAY | 3 | STAD, NPC, PRAD |
