Table 3 Prediction performance of HRD across three models on test set
Model | CT Type | AUC | Accuracy | Sensitivity | Specificity |
|---|---|---|---|---|---|
HCR | 40 kVp | 0.76 [0.69, 0.84] | 69% [62%, 77%] | 66% [60%, 80%] | 71% [57%, 77%] |
80 kVp | 0.70 [0.61, 0.77] | 65% [55%, 68%] | 56% [50%, 70%] | 75% [54%, 74%] | |
Combined | 0.71 [0.64, 0.79] | 65% [57%, 72%] | 66% [53%, 74%] | 65% [53%, 75%] | |
sDL | 40 kVp | 0.85 [0.78, 0.91] | 78% [72%, 84%] | 73% [62%, 82%] | 83% [76%, 91%] |
80 kVp | 0.77 [0.68, 0.84] | 69% [62%, 76%] | 73% [68%, 86%] | 63% [53%, 72%] | |
Combined | 0.82 [0.73, 0.88] | 80% [72%, 85%] | 77% [68%, 86%] | 83% [73%, 90%] | |
FM | 40 kVp | 0.88 [0.82, 0.93] | 76% [70%, 86%] | 66% [59%, 82%] | 87% [76%, 92%] |
80 kVp | 0.88 [0.83, 0.93] | 78% [74%, 86%] | 67% [65%, 84%] | 89% [78%, 93%] | |
Combined | 0.87 [0.81, 0.92] | 77% [70%, 84%] | 73% [62%, 81%] | 81% [74%, 92%] | |
Consensus HCR & FM | 40 kVp (67%) | 0.89 [0.82, 0.95] | 84% [75%, 90%] | 74% [64%, 90%] | 93% [77%, 96%] |
80 kVp (62%) | 0.90 [0.83, 0.96] | 85% [75%, 89%] | 70% [63%, 88%] | 98% [80%, 96%] | |
Combined (61%) | 0.91 [0.84, 0.96] | 85% [75%, 90%] | 80% [65%, 89%] | 89% [79%, 98%] | |
Consensus sDL & FM | 40 kVp (70%) | 0.93 [0.87, 0.98] | 89% [81%, 94%] | 82% [68%, 90%] | 94% [85%, 99%] |
80 kVp (65%) | 0.91 [0.85, 0.96] | 86% [77%, 93%] | 81% [68%, 92%] | 90% [80%, 97%] | |
Combined (71%) | 0.93 [0.87, 0.98] | 90% [84%, 96%] | 88% [77%, 96%] | 92% [87%, 99%] |
