Fig. 3: EPCs modulate immunometabolism.
From: Targeting erythroid progenitor cell metabolism to enhance cancer immunotherapy

EPCs can interact with immune cells and influence their metabolic processes. Alternatively, they may remodel the immune microenvironment by regulating their own metabolism, ultimately impacting antitumor immunity. EPC erythroid progenitor cell, ARG arginase, NK natural killer, PD-L1 programmed death-ligand 1, PD-1 programmed death receptor 1, TGF-β transforming growth factor beta, CTL cytotoxic T lymphocyte, DC dendritic cell, Treg regulatory T cell, TCR T cell receptor, MDSC myeloid-derived suppressor cell, EDMC erythroid-derived myeloid cell.