Table 7 Consistency between extracted histology and IHC/FISH results

		Chromophobe RCC	Papillary RCC	CCPRCT	Clear cell RCC	TFE3 Rearranged RCC	TFEB Altered RCC
Total Number of specimens^a		84	119	62	1630	6	5
CA-IX	*Expected* → Extracted ↓	Negative	Focal/Patchy Positive or Negative	Positive (Cup-Like)	Positive or Positive (Box-Like)	Negative	Negative
	Positive (cup-like)	0	1^d	61	3^d	0	0
	Positive (box-like)	0	0	2^c	164	0	0
	Focal/patchy positive	0	22	0	6^c	0	1
	Other positive^b	0	6	3	548	0	0
	Negative	24	15	0	2^c	5	3
CD117	*Expected* → Extracted ↓	Positive	Negative	Negative	Negative	Negative	Negative
	Positive	87	0	0	1^d	0	1^c
	Negative	0	4	6	26	2	3
Racemase	*Expected* → Extracted ↓	Negative	Positive	Negative	Mixed	Mixed	Mixed
	Focal/patchy positive	0	2	0	7	0	0
	Positive/ diffuse positive	2^c	99	0	9	1	2
	Negative	3	0	13	4	0	0
TFE3	*Expected* → Extracted ↓	Negative	Negative	Negative	Negative	Rearranged	Negative
	Rearranged	0	0	0	0	6	0
	Negative	2	7	0	6	0	4
TFEB	*Expected* → Extracted ↓	Negative	Negative	Negative	Negative	Negative	Rearranged/ Amplified
	Rearranged/ amplified	0	0	0	0	0	5
	Negative	2	6	0	4	6	0

^aSingle specimens may have multiple tests, thus column totals may be higher than the number of specimens.
^bIncludes “Positive” alone, or with other modifiers not explicitly focal/patchy, cup-like, or box-like.
^cReport reviewed and the LLM was correct, thus identifying a typographic mistake in the report free text (Supplementary Table 17 for details).
^dReport reviewed and the LLM found to have made a mistake in either histology or IHC/FISH results (Supplementary Table 17 for details).

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