Table 2 Patient characteristics

From: Digital twin models for predicting venetoclax and azacitidine-induced neutropenia in patients with acute myeloid leukemia

 

Ven-Aza treated patients

Model fitting patients

Train/test patients

# Patients

92

71

33

# Male

53 (58%)

40 (56%)

20 (61%)

# Age ≤75

61 (66%)

47 (66%)

22 (67%)

# Alive

31 (34%)

30 (42%)

20 (61%)

# De Novo AML

48 (52%)

40 (56%)

25 (76%)

# Recurrent, relapse, or secondary AML

44 (48%)

31 (44%)

8 (24%)

# Achieved remission

74 (80%)

66 (93%)

33 (100%)

# Relapsing

42 (46%)

35 (49%)

14 (42%)

Median progression-free survival

232.5 days

329 days

533 days

Median overall survival

395 days

466 days

585 days

Median neutrophil measurements

14.5

19

33

Median bone marrow measurements

5

6

8