Table 1 Characteristic of all esophageal cancer patients stratified by treatment
Overall | Endoscopic therapy | Endoscopic therapy + CRT | Esophagectomy | Esophagectomy + CRT | Chemoradiotherapy | |
|---|---|---|---|---|---|---|
Characteristic | n = 1199 | n = 252 | n = 41 | n = 746 | n = 62 | n = 98 |
Age, n (%) | ||||||
<55 years | 153 (12.76) | 20 (7.94) | 2 (4.88) | 115 (15.42 | 9 (14.52) | 7 (7.14) |
55–65 years | 372 (31.03) | 55 (21.83) | 10 (24.39) | 258 (34.58) | 20 (32.26) | 29 (29.59) |
65–75 years | 418 (34.86) | 84 (33.33) | 13 (31.71) | 264 (35.39) | 55 (36.67) | 33 (33.67) |
75–85 years | 227 (18.93) | 78 (30.95) | 13 (31.71) | 102 (13.67) | 17 (11.33) | 25 (25.51) |
85+ years | 29 (2.42) | 15 (5.95) | 3 (7.32) | 7 (0.94) | 0 (0) | 4 (4.08) |
Sex, n (%) | ||||||
Female | 440 (36.70) | 46 (18.25) | 10 (24.39) | 118 (15.82) | 22 (14.67) | 20 (20.41) |
Male | 759 (63.30) | 206 (81.75) | 31 (75.61) | 628 (84.18) | 128 (85.33) | 78 (79.59) |
Race recode, n (%) | ||||||
White | 1089 (90.83) | 234 (92.86) | 38(92.68) | 679 (91.02) | 133 (88.67) | 81 (82.65) |
Black | 53 (4.42) | 12 (4.76) | 0 (0) | 29 (3.89) | 7 (4.67) | 12 (12.24) |
Other | 57 (4.75) | 6 (2.38) | 3 (7.32) | 38 (5.10) | 10 (6.67) | 5 (5.10) |
Marital status, n (%) | ||||||
Married | 774 (64.55) | 146 (57.94) | 21 (51.22) | 506 (67.83) | 111 (74.00) | 55 (56.12) |
Single | 164 (13.68) | 40 (15.87) | 8 (19.51) | 98 (13.14) | 14 (9.33) | 13 (13.27) |
Other | 261 (21.77) | 66 (26.19) | 12 (29.27) | 142 (19.03) | 25 (16.67) | 30 (30.61) |
Primary Site, n (%) | ||||||
Cervical esophagus | 8 (0.67) | 1 (0.40) | 0 (0) | 3 (0.40) | 0 (0) | 4 (4.08) |
Thoracic esophagus | 36 (3.00) | 7 (2.78) | 1 (2.44) | 25 (3.35) | 1 (0.67) | 3 (3.06) |
Abdominal esophagus | 11 (0.92) | 1 (0.40) | 0 (0) | 9 (1.21) | 1 (0.67) | 0 (0) |
Upper third of esophagus | 29 (2.42) | 6 (2.38) | 2 (4.88) | 9 (1.21) | 4 (2.67) | 9 (9.18) |
Middle third of esophagus | 146 (12.18) | 29 (11.51) | 2 (4.88) | 92 (12.33) | 14 (9.33) | 18 (18.37) |
Lower third of esophagus | 892 (74.40) | 189 (75.00) | 35 (85.37) | 562 (75.34) | 119 (79.33) | 55 (56.12) |
Overlapping lesion of esophagus | 15 (1.25) | 1 (0.40) | 0 (0) | 11 (1.47) | 2 (1.33) | 3 (3.06) |
Esophagus, NOS | 62 (5.17) | 18 (7.14) | 1 (2.44) | 35 (4.69) | 9 (6.00) | 6 (6.12) |
Tumor grade, n (%) | ||||||
Grade I | 185 (177.01) | 45 (17.86) | 5(12.20) | 121 (16.22) | 13 (8.67) | 8 (8.16) |
Grade II | 593 (553.03) | 131 (51.98) | 17 (41.46) | 378 (50.67) | 57 (38.00) | 40 (40.82) |
III–IV | 319 (26.61) | 42 (16.67) | 15 (36.59) | 212 (28.42) | 66 (44.00) | 28 (28.57) |
Unknown | 102 (8.51) | 34 (13.49) | 4 (9.76) | 35 (4.69) | 14 (9.33) | 22 (22.45) |
Tumor size, n (%) | ||||||
>2 cm | 360 (30.02) | 30 (11.90) | 8 (19.51) | 262 (35.12) | 56 (37.33) | 33 (33.67) |
≤ 2 cm | 839 (69.97) | 222 (88.10) | 33 (80.49) | 484 (64.88) | 94 (62.67) | 65 (66.33) |
Histology, n (%) | ||||||
Squamous | 188 (15.68) | 27 (10.71) | 8 (19.51) | 102 (13.67) | 27 (18.00) | 38 (38.78) |
Adenocarcinoma | 999 (83.32) | 218 (86.51) | 33 (80.49) | 642 (86.06) | 119 (79.33) | 58 (59.18) |
Other | 12 (1.00) | 7 (2.78) | 0 (0) | 2 (0.27) | 4 (2.67) | 2 (2.04) |
DTTT, n (%) | ||||||
<1 months | 246 (20.52) | 92 (36.51) | 11 (26.83) | 120 (16.09) | 18 (29.03) | 5 (5.10) |
1–3 months | 692 (57.71) | 113 (44.84.) | 22 (53.66) | 452 (60.59) | 34 (54.84) | 71 (72.45) |
3–6months | 231 (19.27) | 37 (14.68) | 8 (19.51) | 158 (21.18) | 10 (16.13) | 18 (18.37) |
≥6 months | 30 (2.50) | 10 (3.97) | 0 (0) | 16 (2.14) | 0 (0) | 4 (4.08) |
MHI, n (%) | ||||||
<$35,000 | 12 (1.00) | 1 (0.40) | 0 (0) | 3 (0.40) | 4 (2.67) | 4 (4.08) |
$35,000– $44,999 | 55 (4.59) | 6 (2.38) | 1 (2.44) | 34 (4.56) | 6 (0.40) | 11 (11.22) |
$45,000– $54,999 | 126 (10.51) | 26 (10.32) | 5 (12.20) | 79 (10.59) | 18 (12.00) | 11 (11.22) |
$55,000– $64,999 | 217 (18.10) | 52 (20.63) | 5 (12.20) | 123 (16.49) | 28 (18.67) | 26 (26.53) |
$65,000– $74,999 | 314 (26.19) | 65 (25.79) | 15 (36.59) | 205 (27.48) | 38 (25.33) | 20 (20.41) |
$75,000+ | 475 (39.62) | 102 (40.48) | 15 (36.59) | 302 (40.48) | 56 (37.33) | 26 (26.53) |
Cause of death, n (%) | ||||||
Alive | 577 (48.12) | 119 (47.2) | 14 (34.15) | 403 (54.02) | 66 (44.00) | 16 (16.33) |
Died, cancer | 334 (27.86) | 41 (16.27) | 12 (29.27) | 201 (26.94) | 57 (38.00) | 58 (59.18) |
Died, other cause | 288 (24.02) | 92 (36.51) | 15 (36.59) | 142 (19.03) | 27 (18.00) | 24 (24.49) |
Survival months | ||||||
Median (IQR) | 67.00[35.00,112.00] | 67.00[35.00,111.00] | 36.00[15.00,59.50] | 81.50[43.00, 130.00] | 76.50[41.50,114.50] | 21.00[9.00,45.25] |
