Table 1 Selected federated data networks for epidemiology and RWE across the globe
Federated network | Hosting organization and type | Data type and geography | Primary section domain |
|---|---|---|---|
Sentinel System | US Food and Drug Administration (Government) | Medical claims and electronic health records (EHRs) | Medical product safety surveillance |
National Patient-Centered Clinical Research Network (PCORnet) | Patient-Centered Outcomes Research Institute (Non-profit organization) | EHRs | Scientific and clinical research, including pragmatic trials |
Genomic Information Commons | Boston Children’s Hospital (Non-profit organization) | EHRs and genomic data | Scientific and clinical research in pediatrics |
Pediatric Emergency Care and Applied Research Network (PECARN) | University of Utah (Academia) | EHRs | Scientific and clinical research in pediatrics |
Informatics for Integrating Biology & the Bedside (i2b2) | Harvard university (Academia) | EHRs | Translational research |
Observational Health Data Sciences and Informatics (OHDSI) | Columbia University (Academia) | Medical claims and EHRs | Scientific and clinical research |
Data Analysis and Real World Interrogation Network (DARWIN-EU) | European Medicine Agency (Government) | EHRs | Medical product safety surveillance |
European Health Data and Evidence Network (EHDEN) | Erasmus University Medical Center (Academia) | EHRs | Scientific and clinical research |
Canadian Network for Observational Drug Effects Studies (CNODES) | Canada’s Drug Agency (Government) | Medical claims and EHRs | Medical product safety surveillance |
